منابع مشابه
PTC taste threshold distributions and age in Mennonite populations.
A number of tlutlic* rrjwrt an impairment of the genetically inherited ability to taste ITC a.% a function of age. but ignore the cumulative effect of smoking on taste deterioration. Thi* «tudy examine* the effect of aging on taste sensitivity in nonsmoking: Mennonite population*. The results obtained preclude a cause and effect relationship between age and ITC taste sensitivity. These results ...
متن کاملNonequilibrium statistical mechanics of dividing cell populations.
We present and study a model for the nonequilibrium statistical mechanics of protein distributions in a proliferating cell population. Our model describes how the total protein variation is shaped by two processes: variation in protein production internal to the cells and variation in division and inheritance at the population level. It enables us to assess the contribution of each of these com...
متن کاملDividing loyalties: caring for individuals and populations.
Are health maintenance organization (HMO) physicians obligated to act exclusively in the interest of the individual patient? Does the mere existence of financial incentives to limit patient care violate this obligation? To what extent are doctors responsible for the population of patients served by a health plan, or for promoting a fair distribution of health care among society as a whole? Thes...
متن کاملFitness distributions in exponentially growing asexual populations.
We explore a mean-field model for the evolution of exponentially growing populations of mutating replicators. Motivated by recent in vitro experiments devised to analyze phenotypic properties of bacterial and viral populations subjected to serial population transfers, we allow our in silico individuals to undergo unrestricted growth before applying bottleneck events. Different dynamical regimes...
متن کاملDynamics of protein distributions in cell populations.
A population of cells exhibits wide phenotypic variation even if it is genetically homogeneous. In particular, individual cells differ from one another in the amount of protein they express under a given regulatory system under fixed conditions. Here we study how protein distributions in a population of the yeast S. cerevisiae are shaped by a balance of processes: protein production--an intrace...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1967
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(67)86575-5